ONE POT SYNTHESIS OF PYRANOPYRAZOLES USING SODIUM LACTATE AS AN EFFICIENT CATALYST
An efficient one pot synthesis of pyranopyrazoles has been achieved by the four-component condensation of hydrazine hydrate, ethyl
acetoacetate, aldehydes and malononitrile using sodium lactate as a catalyst in aqueous ethanolic medium under reflux condition. The
method is simple and green to afford pyranopyrazoles in a short time. It provides a new base catalyst that readily gives product from
moderate to excellent yields.