My Blog

THE EXPEDITIOUS OXIDATION OF ARYLBORONIC ACIDS TO PHENOLS BY TERTIARY BUTYL HYDROPEROXIDE IN GREEN AQUEOUS ETHANOL

THE EXPEDITIOUS OXIDATION OF ARYLBORONIC ACIDS TO PHENOLS BY TERTIARY BUTYL HYDROPEROXIDE IN GREEN AQUEOUS ETHANOL

Author: Ayaz Mahmood Dar, Nisar A Dangroo, Shafia Mir, Bashir Ahmad Dar
Abstract

An efficient protocol for the synthesis of phenols from arylboronic acids has been developed by using t-butyl hydroperoxide (TBHP) as oxidant in water-ethanol as a binary reaction medium. The reaction is metal and additive free and does not require strong basic conditions. The developed protocol has a broad substrate scope and functional group compatibility. Notably the mild conditions, shorter reaction time, good to excellent yields and eco-friendly reaction medium are some important features of the developed method.

Keywords:

Leave a Comment

Your email address will not be published. Required fields are marked *