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A CONVENIENT CATALYST-FREE SYNTHESIS OF SOME SUBSTITUTED PYRIDINE BENZAMIDES FROM ARYL ALDEHYDES

A CONVENIENT CATALYST-FREE SYNTHESIS OF SOME SUBSTITUTED PYRIDINE BENZAMIDES FROM ARYL ALDEHYDES

Author: Vaishanavi S. Jambhorkar, Aniket P. Sarkate, Aishwarya P. Rajhans, Kshipra S. Karnik, Sajed H. Ansari, Shambala U. Chavan,Yogesh W. More, Dattatraya N. Pansare
Abstract

A new method of amides synthesis under catalyst-free condition has been developed by using aldehydes and aminopyridines. The amides were synthesized by using different aldehydes and aminopyridines using ethanol as a solvent and hydrogen peroxide as oxidant. The method helps in preparation of amides which were acquired in good yield within 4-5 h using conventional heating. The reaction is catalystfree. The developed method is easy, economical, and flexible.

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