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ONE POT SYNTHESIS OF PYRANOPYRAZOLES USING SODIUM LACTATE AS AN EFFICIENT CATALYST

ONE POT SYNTHESIS OF PYRANOPYRAZOLES USING SODIUM LACTATE AS AN EFFICIENT CATALYST

Author: J. P. Sonar, S. D. Pardeshi, S. A. Dokhe, G. M. Bhavar, S. U. Tekale, A. M. Zine, S. N. Thore
Abstract

An efficient one pot synthesis of pyranopyrazoles has been achieved by the four-component condensation of hydrazine hydrate, ethyl
acetoacetate, aldehydes and malononitrile using sodium lactate as a catalyst in aqueous ethanolic medium under reflux condition. The
method is simple and green to afford pyranopyrazoles in a short time. It provides a new base catalyst that readily gives product from
moderate to excellent yields.

Keywords: catalyst; green synthesis; one pot; pyranopyrazole; sodium lactate

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