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2022, Vol: 11, Issue: 4
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Research Article 
ECB. 2020; 9(7): 179-183


MICROWAVE-INDUCED, EFFICIENT, CONVENIENT AND RAPID SYNTHESIS OF BENZYLOXYCHALCONES AS POTENT GROWTH INHIBITOR

Nagesh Deshmukh, Sainath Zangade, Avinash Shinde.

Abstract
A novel series of substituted chalcones containing benzyloxy moiety (3a-3h) was synthesized by microwave induced Claisen-Schmidt condensation of 2-acetyl-1-naphthol and its halo derivatives with different substituted aromatic aldehydes. All the synthesized chalcones were characterized by spectral analysis and screened for their antibacterial and antifungal effectiveness by using standard methods. It is found that the microwave irradiation technique is superior in terms of considerable increase in the reaction rate, yields and shortening the reaction time. The investigation of antimicrobial screening revealed that compounds (3a-3d) containing benzyloxy group at para position of aldehyde ring of chalcones possessing more potent antimicrobial activity.

Key words: Chalcones; Claisen-Schmidt condensation; microwave irradiation; antibacterial activity; antifungal activity.


 
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How to Cite this Article
Pubmed Style

Nagesh Deshmukh, Sainath Zangade, Avinash Shinde. MICROWAVE-INDUCED, EFFICIENT, CONVENIENT AND RAPID SYNTHESIS OF BENZYLOXYCHALCONES AS POTENT GROWTH INHIBITOR. ECB. 2020; 9(7): 179-183.

Web Style

Nagesh Deshmukh, Sainath Zangade, Avinash Shinde. MICROWAVE-INDUCED, EFFICIENT, CONVENIENT AND RAPID SYNTHESIS OF BENZYLOXYCHALCONES AS POTENT GROWTH INHIBITOR. https://www.eurchembull.com/?mno=47643 [Access: August 09, 2022].

AMA (American Medical Association) Style

Nagesh Deshmukh, Sainath Zangade, Avinash Shinde. MICROWAVE-INDUCED, EFFICIENT, CONVENIENT AND RAPID SYNTHESIS OF BENZYLOXYCHALCONES AS POTENT GROWTH INHIBITOR. ECB. 2020; 9(7): 179-183.


Vancouver/ICMJE Style

Nagesh Deshmukh, Sainath Zangade, Avinash Shinde. MICROWAVE-INDUCED, EFFICIENT, CONVENIENT AND RAPID SYNTHESIS OF BENZYLOXYCHALCONES AS POTENT GROWTH INHIBITOR. ECB. (2020), [cited August 09, 2022]; 9(7): 179-183.


Harvard Style

Nagesh Deshmukh, Sainath Zangade, Avinash Shinde (2020) MICROWAVE-INDUCED, EFFICIENT, CONVENIENT AND RAPID SYNTHESIS OF BENZYLOXYCHALCONES AS POTENT GROWTH INHIBITOR. ECB, 9 (7), 179-183.


Turabian Style

Nagesh Deshmukh, Sainath Zangade, Avinash Shinde. 2020. MICROWAVE-INDUCED, EFFICIENT, CONVENIENT AND RAPID SYNTHESIS OF BENZYLOXYCHALCONES AS POTENT GROWTH INHIBITOR. European Chemical Bulletin, 9 (7), 179-183.


Chicago Style

Nagesh Deshmukh, Sainath Zangade, Avinash Shinde. "MICROWAVE-INDUCED, EFFICIENT, CONVENIENT AND RAPID SYNTHESIS OF BENZYLOXYCHALCONES AS POTENT GROWTH INHIBITOR." European Chemical Bulletin 9 (2020), 179-183.


MLA (The Modern Language Association) Style

Nagesh Deshmukh, Sainath Zangade, Avinash Shinde. "MICROWAVE-INDUCED, EFFICIENT, CONVENIENT AND RAPID SYNTHESIS OF BENZYLOXYCHALCONES AS POTENT GROWTH INHIBITOR." European Chemical Bulletin 9.7 (2020), 179-183. Print.


APA (American Psychological Association) Style

Nagesh Deshmukh, Sainath Zangade, Avinash Shinde (2020) MICROWAVE-INDUCED, EFFICIENT, CONVENIENT AND RAPID SYNTHESIS OF BENZYLOXYCHALCONES AS POTENT GROWTH INHIBITOR. European Chemical Bulletin, 9 (7), 179-183.


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