E-ISSN 2063-5346
 

Research Article 
ECB. 2017; 6(7): 292-294


ISOLATION AND ANTIMICROBIAL ANALYSIS OF A STEROIDAL TERPENE FROM THE BUTANOL FRACTION OFBYROPHYLLUM PINNATUM (LAM.) OKEN

Olawale H. Oladimeji, Kufre E. Eberefiak.

Abstract
Bryophyllum pinnatum (Lam.) Oken is a plant used in treatment/management of ear-ache, cough, gastro-intestinal disorders and inflammation. Prior to this study, reports of the isolation of cardiac glycosides from the ethyl-acetate fraction of the plant abound. However, very scanty or no literature exists on other organic fractions from where chemical constituents could also be obtained. Hence, the chemical and biological properties of the butanol fraction of the plant were studied. The silica gel column chromatography of the fraction led to a steroidal terpene whose identity has been revealed to be 3-hydroxy-(3β, 17β)-spiro(androst-5-ene-17,1ʹ-cyclobutan)-2ʹ-one using the MS and IR spectral techniques. This compound was strongly bacteriostatic against Staphylococcus aureus and Candida albican sbut recorded no activity against Escherichia coli.

Key words: Butanol, chromatography, terpene, bacteriostatic, Bryophyllum pinnatum.


 
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Pubmed Style

Olawale H. Oladimeji, Kufre E. Eberefiak. ISOLATION AND ANTIMICROBIAL ANALYSIS OF A STEROIDAL TERPENE FROM THE BUTANOL FRACTION OFBYROPHYLLUM PINNATUM (LAM.) OKEN . ECB. 2017; 6(7): 292-294.


Web Style

Olawale H. Oladimeji, Kufre E. Eberefiak. ISOLATION AND ANTIMICROBIAL ANALYSIS OF A STEROIDAL TERPENE FROM THE BUTANOL FRACTION OFBYROPHYLLUM PINNATUM (LAM.) OKEN . https://www.eurchembull.com/?mno=41768 [Access: November 29, 2022].


AMA (American Medical Association) Style

Olawale H. Oladimeji, Kufre E. Eberefiak. ISOLATION AND ANTIMICROBIAL ANALYSIS OF A STEROIDAL TERPENE FROM THE BUTANOL FRACTION OFBYROPHYLLUM PINNATUM (LAM.) OKEN . ECB. 2017; 6(7): 292-294.



Vancouver/ICMJE Style

Olawale H. Oladimeji, Kufre E. Eberefiak. ISOLATION AND ANTIMICROBIAL ANALYSIS OF A STEROIDAL TERPENE FROM THE BUTANOL FRACTION OFBYROPHYLLUM PINNATUM (LAM.) OKEN . ECB. (2017), [cited November 29, 2022]; 6(7): 292-294.



Harvard Style

Olawale H. Oladimeji, Kufre E. Eberefiak (2017) ISOLATION AND ANTIMICROBIAL ANALYSIS OF A STEROIDAL TERPENE FROM THE BUTANOL FRACTION OFBYROPHYLLUM PINNATUM (LAM.) OKEN . ECB, 6 (7), 292-294.



Turabian Style

Olawale H. Oladimeji, Kufre E. Eberefiak. 2017. ISOLATION AND ANTIMICROBIAL ANALYSIS OF A STEROIDAL TERPENE FROM THE BUTANOL FRACTION OFBYROPHYLLUM PINNATUM (LAM.) OKEN . European Chemical Bulletin, 6 (7), 292-294.



Chicago Style

Olawale H. Oladimeji, Kufre E. Eberefiak. "ISOLATION AND ANTIMICROBIAL ANALYSIS OF A STEROIDAL TERPENE FROM THE BUTANOL FRACTION OFBYROPHYLLUM PINNATUM (LAM.) OKEN ." European Chemical Bulletin 6 (2017), 292-294.



MLA (The Modern Language Association) Style

Olawale H. Oladimeji, Kufre E. Eberefiak. "ISOLATION AND ANTIMICROBIAL ANALYSIS OF A STEROIDAL TERPENE FROM THE BUTANOL FRACTION OFBYROPHYLLUM PINNATUM (LAM.) OKEN ." European Chemical Bulletin 6.7 (2017), 292-294. Print.



APA (American Psychological Association) Style

Olawale H. Oladimeji, Kufre E. Eberefiak (2017) ISOLATION AND ANTIMICROBIAL ANALYSIS OF A STEROIDAL TERPENE FROM THE BUTANOL FRACTION OFBYROPHYLLUM PINNATUM (LAM.) OKEN . European Chemical Bulletin, 6 (7), 292-294.