E-ISSN 2063-5346
 

Research Article 
ECB. 2021; 10(2): 103-106


GLOBAL APPROACHES TO IMMUNITY AND EPIDEMIOLOGICAL STUDIES OF SARS-COV-2: DOES UNIVERSAL BCG VACCINATION POLICY PLAY A ROLE ?’

Smriti Sharma, Vinayak Bhatia.

Abstract
It has been observed that countries without universal policies of BCG vaccination are more severely affected compared to countries with long-established BCG vaccination policies. This has led researchers to investigate the possible relation between BCG and COVID-19. The authors have evaluated the current research regarding the role of the universal Bacille Calmette Guerin (BCG) vaccination policy of a country to the morbidity and mortality due to COVID-19/ SARS-CoV-2 in that country. It is believed that the BCG vaccine trains the immune system of the human body for non-mycobacterial pathogens through non-specific immunotherapeutic mechanisms. Most of the epidemiological studies point towards a positive correlation but barring a few, and they tend to ignore factors like lower testing rates in countries having universal BCG policy. BCG vaccination policy cannot be seen in isolation as the factors like climatic conditions, nutritional habits, genetic and ethnic aspects, social and cultural influence and age distribution also are responsible for the varied morbidity and mortality due to COVID-19. Multiple-dose BCG vaccine repurposing for SARS-CoV-2, however, should be explored. Clinical trials of the BCG vaccine to test its efficacy on SARS-CoV-2 are urgently needed before deducing unidirectional correlations.

Key words: SARS-CoV-2; Universal BCG vaccination policy; COVID-19; Coronavirus; Morbidity; Mortality


 
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Pubmed Style

Smriti Sharma, Vinayak Bhatia. GLOBAL APPROACHES TO IMMUNITY AND EPIDEMIOLOGICAL STUDIES OF SARS-COV-2: DOES UNIVERSAL BCG VACCINATION POLICY PLAY A ROLE ?’. ECB. 2021; 10(2): 103-106.


Web Style

Smriti Sharma, Vinayak Bhatia. GLOBAL APPROACHES TO IMMUNITY AND EPIDEMIOLOGICAL STUDIES OF SARS-COV-2: DOES UNIVERSAL BCG VACCINATION POLICY PLAY A ROLE ?’. https://www.eurchembull.com/?mno=46518 [Access: August 09, 2022].


AMA (American Medical Association) Style

Smriti Sharma, Vinayak Bhatia. GLOBAL APPROACHES TO IMMUNITY AND EPIDEMIOLOGICAL STUDIES OF SARS-COV-2: DOES UNIVERSAL BCG VACCINATION POLICY PLAY A ROLE ?’. ECB. 2021; 10(2): 103-106.



Vancouver/ICMJE Style

Smriti Sharma, Vinayak Bhatia. GLOBAL APPROACHES TO IMMUNITY AND EPIDEMIOLOGICAL STUDIES OF SARS-COV-2: DOES UNIVERSAL BCG VACCINATION POLICY PLAY A ROLE ?’. ECB. (2021), [cited August 09, 2022]; 10(2): 103-106.



Harvard Style

Smriti Sharma, Vinayak Bhatia (2021) GLOBAL APPROACHES TO IMMUNITY AND EPIDEMIOLOGICAL STUDIES OF SARS-COV-2: DOES UNIVERSAL BCG VACCINATION POLICY PLAY A ROLE ?’. ECB, 10 (2), 103-106.



Turabian Style

Smriti Sharma, Vinayak Bhatia. 2021. GLOBAL APPROACHES TO IMMUNITY AND EPIDEMIOLOGICAL STUDIES OF SARS-COV-2: DOES UNIVERSAL BCG VACCINATION POLICY PLAY A ROLE ?’. European Chemical Bulletin, 10 (2), 103-106.



Chicago Style

Smriti Sharma, Vinayak Bhatia. "GLOBAL APPROACHES TO IMMUNITY AND EPIDEMIOLOGICAL STUDIES OF SARS-COV-2: DOES UNIVERSAL BCG VACCINATION POLICY PLAY A ROLE ?’." European Chemical Bulletin 10 (2021), 103-106.



MLA (The Modern Language Association) Style

Smriti Sharma, Vinayak Bhatia. "GLOBAL APPROACHES TO IMMUNITY AND EPIDEMIOLOGICAL STUDIES OF SARS-COV-2: DOES UNIVERSAL BCG VACCINATION POLICY PLAY A ROLE ?’." European Chemical Bulletin 10.2 (2021), 103-106. Print.



APA (American Psychological Association) Style

Smriti Sharma, Vinayak Bhatia (2021) GLOBAL APPROACHES TO IMMUNITY AND EPIDEMIOLOGICAL STUDIES OF SARS-COV-2: DOES UNIVERSAL BCG VACCINATION POLICY PLAY A ROLE ?’. European Chemical Bulletin, 10 (2), 103-106.