In 2020 to 2021 the new research in the pharmacy and biotechnology field increases rapidly. The research of artificial intelligence (AI) in medical science also opened a new platform after the covid pandemic. Many companies are also investing huge amounts of money to newer vaccine and New Drug Delivery Systems (NDDS) associated with artificial intelligence. Computed tomography (CT) scan and magnetic resonance imaging (MRI) are two important tools for prosthetics preparations. Newer engineering has the capability for the preparation of novel dosage forms as target delivery system. However, the formulation of NDDS at commercial scale is limited to quite a bit and the factories are still producing the oral drug delivery system, mainly with controlled-release tablets. The application of AI and 3D printing technology in the pharma industry has brought into being a new purview in the delving of manufacturing for replacing and repairing the defected organs like kidneys, heart, eyes, lungs, etc. In this article, we are deliberating the perspective role of AI and 3D printing in the manufacturing of pharmaceuticals.