This study is designed to evaluate the orthodontic rate of space closure after first premolar extraction between canine and 1st molar. It comprises of four different techniques of closure of space by power E chain, active tieback, NiTi closed coil spring and mini screw attached with E chain. Materials and Methods: In this study there were 20 sample patient which is distributed uniformly in 4 groups, 5 for E chain, 5 for active tieback, 5 for NiTi closed coil spring and 5 for mini screw attached to E chain. After the levelling and alignment 0.019x 0.025 ss wire placed for one month then maxillary and mandibular study model were collected at start of space closure (T0) and four month later (T1). Space present in all four quadrant was measured, and calibrated by examiner using vernier callipers at T0 and T1 The rate of space closure, in millimetre per month and 4 monthly rates, was then calculated. Koden 9 mm NiTi spring having 200 gm forces is used to retract canine. Sk surgical 1.5 x 9 mm screw is used to retract the canine. Mini implant was placed in the buccal interradicular space between the second premolar and the first molar in maxillary andmandibular arches. The data was entered into the excel sheet. The data was analysed using SPSS (Statistical Package for Social Sciences) 20.0 version. The data was analysed for probability distribution using Kolmogorov-Smirnov test. The intra-group comparison was done using paired ‘t’ test. The inter-group comparison was done using One-way ANOVA followed by post hoc analysis. Results: The study included 20 sample specimens belonging to 4 groups based on the type of space closure method used. Group 1- NiTi closed coil spring, Group 2- Active tie back, Group 3- Power E chain, Group 4- Mini screw with E chain. Post hoc analysis revealed that the rate of space closure in group 1 was significantly more than that in group 2. rate of space closure was non-significantly different between group 1 and group 3, group 1 and group 4, group 2 and group 3and between group 3 and group 4 (p value>0.05). Conclusion: Our study has shown that NiTi springs delivering 200gm forces gave the most rapid rate of space closure and may be considered the treatment of choice. Mini screw with polyurethane powerchain is best for anchorage and its rate of space closure is non-significant with polyurethane power chain but its rate of space closure is less than NiTi closed coil spring. But at the same time, it is expensive and require surgical exposure to the patient.