Introduction: Intestinal parasitic infections like Giardia intestinalis, Entamoeba histolytica, and coccidian parasites such as Cryptosporidium parvum are parasites causes diarrhoea in immunocompromised individuals, and cause morbidity and mortality worldwide. The various diagnostic modalities for detection of Cryptosporidium parvumare microscopy, ICT, ELISA and PCR. Objective: To detect Cryptosporidium parvum in stool samples of immunocompromised patients (HIV infection) by ICT and modified ZN staining techniques. Material & Methods: The study was conducted in the Department of Microbiology & Medicine from July 2022 to April 2023 in RMCH&RC, Kanpur. Total 50 stool samples were collected from the symptomatic patients (HIV) to detect Cryptosporidium parvum samples were stained with modified ZN staining and ICT. Result: Out of the total 50 stool samples of HIV patients 31(62%)were males and 19(38%)females. 6(12%) were positive for Cryptosporidium parvumin in which age group of (31-40 years) were detected by ICT,only 4(66.66%) were positive by modified ZN staining. The sensitivity wasfound to be (66.7%), specificity(95.6%), PPV(66.7%) and NPV(95.6%) of modified ZN staining. The sensitivity was found to be (99.0%), specificity(100%), PPV(99.0%) and NPV(100%) of ICT. Conclusion: In this study the incidence of Cryptosporidium parvum was found to be 12%. ICT being more effective than modified ZN staining. Therefore, the new ICT kit being rapid and relevant method for detection of Cryptosporidium.