.

ISSN 2063-5346
For urgent queries please contact : +918130348310

A Comparative Study of Dexmedetomidine and Clonidine as Adjuvants to Ropivacaine 0.75% for Epidural Anaesthesia in Patients Undergoing Lower Limb Orthopedic Surgeries

Main Article Content

Dr. Lokeshwari Divya J, Dr. Balamurugan B, Dr. K Vijayaragavan, Dr Anand S
» doi: 10.48047/ecb/2023.12.1.372

Abstract

Over the last few decades, anaesthetic techniques used during the surgery have evolved and improved drastically. Many new drugs have been introduced which help in reducing the anxiety of the patients. Epidural anaesthesia is very popularly used in lower abdominal as well as lower limb surgeries. Ropivacaine has less cardiac toxicity and hence can be used as an ideal local anaesthetic for epidural anaesthesia. Methodology: A study was conducted at Chettinad Hospital and Research Institute, Chennai. A total of 100 patients belonging to ASA I and ASA II (American Society of Anaesthesiologists) were enrolled and divided into two groups based on the inclusion and exclusion criteria. Group A received 0.75% ropivacaine with clonidine (1 mcg/kg) with a total volume of 20 ml while Group B received 0.75% ropivacaine with dexmeditomidine (1 mcg/kg) with a total volume of 20 ml. Results: Clonidine to Ropivacaine, showed statistically significant difference in the onset of sensory and motor blockade between Ropivacaine with clonidine and Ropivacaine with dexmedetomidine group. Ropivacaine and dexmedetomidine group produced more intense motor blockade than Ropivacaine with clonidine group. Duration of sensory block is prolonged with ropivacaine and dexmedetomidine group compared to Ropivacaine with clonidine group. Duration of motor block is also prolonged with ropivacaine and dexmedetomidine group compared to Ropivacaine and clonidine group. Conclusion: The addition of the dexmeditomidine 1mcg/kg to 0.75% ropivacaine solution in epidural anaesthesia showed early onset of sensory and motor blockade and prolonged the duration of analgesia when compared to Ropivacaine with clonidine.

Article Details