Gastrointestinal Interventional procedures such as endoscopic retrograde cholangio pancreatography(ERCP) or esophagogastroduodenoscopy (EGD) are complex procedures which make the patient uncomfortable and hence requiring sedation.1 Performing gastrointestinal (GI) endoscopic procedures under sedation has gained popularity and there have been many efforts to investigate the ideal drug regimen and appropriate depth of sedation for the procedures .1 Propofol, the most popular agent used for these procedures has a narrow therapeutic window-ranging from mild sedation to deep general anaesthesia rapidly.2,3