The literature extensively discusses the lipid-based drug delivery strategy for improving drug solubility, permeability and bioavailability. The great majority of new pharmacologically active substances developed in current drug discovery programmes are lipophilic and poorly soluble, which creates a substantial challenge for pharmaceutical researchers tries to increase the oral bioavailability of such therapeutic molecules. Drugs with poor dissolution rate and insufficient absorption can be administered using self-nanoemulsifying drug delivery system (SNEDDS), which is effective oil-based method. Ever since the progress of SNEDDS, researchers have been concentrating on the difficulties of BCS Class II and Class IV pharmaceuticals for increasing water Solubility of poorly water-soluble pharmaceuticals.