Acne is an extremely widespread skin ailment, accounting for a significant cutaneous and psychological disease load. It is distinguished through scaly red skin, papules, freckles and whiteheads, nodules, which and pimples. Acne pathophysiology and modern therapies are problematic to comprehend. Acne prevalence differs greatly between individuals, and genetic predisposition plays a significant role in its development. The pus-forming bacterium Propionibacterium acnes has been related to acne inflammation. (P. acne). The goal of this research was to evaluate the antimicrobial properties of Indian medicinal plants in opposition to the compounds responsible for acne vulgaris. Pathogenic reasons consist of increased production of sebum, pilosebaceous duct hyper cornification, abnormal bacterial function, and irritation. The procedure requires a year of taking synthetic medications, which can have severe side effects. As a consequence, gentler and safer drugs must be used in treatment. Herbal or herbal-based medications are secure substitutes to pharmaceuticals that use natural extracts. The goal of botanical medicine is to provide people with medicines that are effective, safe, efficient, and inexpensive. The present review summarizes the role of herbs in acne treatment. A variety of databases were searched in order to identify everything varieties of medicinal plants with anti-acne action.