The advanced dentistry emphasis on the utilization of cutting-edge materials and manufacturing techniques. Recently, Polyoxymethylene (POM)- a thermoplastic polymerwas investigated as a potential material for denture base. It has exceptional mechanical, chemical, and biocompatibility qualities. Though the material is highly evaluated in literature it is used less in clinical dentistry and fewer clinical reports are available. This material was tried as interim prosthesis for a preliminary report. This pilot report details on a novel technique of fused deposition modelling in fabricating a maxillary denture with a POM denture base. It has significant advantages over other standard materials and technique. This process of creating prostheses with 3D printing is quick, effective, and offers a variety of customizing choices.