The objective of this retrospective study was to assess the safety, feasibility, and clinical outcomes of early laparoscopic cholecystectomy in patients with acute calculous cholecystitis, based on a review of 50 cases. Methods: This study evaluated 50 patients who underwent early laparoscopic cholecystectomy for acute calculous cholecystitis at our institution between 2022 and 2023. Key parameters considered included operative time, conversion to open cholecystectomy, postoperative complications, length of hospital stay, and readmission rates. Results: The average operative time was between 60-90 minutes, with 60% of surgeries completed in under an hour. Conversion to open cholecystectomy was necessary in 10% of cases. Postoperative complications occurred in 6% of patients, predominantly consisting of surgical site infections and abdominal pain. The mean hospital stay was less than 3 days for 76% of patients, with the majority being discharged within this timeframe. Readmission rates within 30 days post-surgery stood at 4%. Conclusion: This study suggests that early laparoscopic cholecystectomy is a feasible and safe strategy for managing acute calculous cholecystitis, with acceptable rates of complications and conversions to open surgery. However, further large-scale, randomized trials are necessary to validate these results and to establish early laparoscopic cholecystectomy as the standard care for acute calculous cholecystitis.