Objective: This study aimed to gather important information for treatment and preventive plans by examining the prevalence, traits, and risk factors of intraoperative acquired pressure injuries (IAPI) in surgical patients. Methods: This retrospective analysis included 342 patients who underwent surgery at our tertiary care hospital between February 1, 2022, and July 31, 2022. The CORN Intraoperative Acquired Pressure Injury Risk Assessment Scale was used to gather information on patient demographics, surgery, and intraoperative variables. There were three types of logistic regression analysis: descriptive, univariate, and multivariate. Results: The incidence of IAPI in surgical patients was 14%, with stage I disease being the most common (76.19%). The most frequently affected sites were the sacrococcygeal region (30.95%), foot (21.43%), and head and face (11.90%). Risk factors for IAPI included anesthesia classification, skin condition at the pressure site, preoperative limb activity, planned operative time, high-risk disease (diabetes), temperature loss, and actual operative time. Conclusions: Intraoperatively acquired pressure injuries are associated with multiple risk factors. Individualized preventive measures for high-risk patients are recommended to reduce the incidence of IAPI.