Zinc and iron are essential micro nutrients required for growth and health. Deficiencies of these nutrients are highly prevalent among populations, but can be alleviated by Nutritional supplementation. Many Cross-sectional studies in humans showed positive association of serum zinc levels with haemoglobin and markers of iron status.Zinc and iron are dietary essential trace elements. Zinc and iron interact competitively during intestinal absorption. Excess of Iron and Zinc inhibits each other. Association of Zinc and iron is important to assess in anaemic condition. Unfortunately few studies are available on absorption of iron in relation to zinc status .in humans, this review article is to Shed light on association between Zinc and iron to treat Anaemia