The new information technology-based health care service known as "e-Health" has previously drawn a lot of scholarly interest. What can we infer about the past research? Using the e-Health-related scientific literature from the Web of Science core database, this article examines how earlier work has evolved. Our thorough examination leads us to believe that 1) IT adoption is the most crucial area for research in this area, 2) Research methodologies are becoming more varied, and 3) Research themes are relatively distinct.