Nowadays, there is a demand for the creation and development of innovative dosage forms in order to increase patient compliance, safety, and efficacy. Mucoadhesive buccal film is a unique film technology that meets all of these characteristics. Traditional oral dosage forms are susceptible to first pass metabolism and degradation caused by enzymes, but mucoadhesive films can avoid first pass metabolism and associated deterioration. Delivery through transmucosal products benefits the absorption 4 times than that of the skin. It provides greater patient compliance without the danger of choking in paediatric and elderly patients. The present paper intends to emphasize the basic methodologies, importance of transmucosal drug delivery and also highlights on the latest advancements in the field