The aim of the study was to investigate the impact of comprehensive quality standards on enhancing the productivity efficiency of healthcare staff in the Saudi government healthcare sector in Riyadh. The study employed a descriptive analytical approach to achieve its objectives. The study sample consisted of 265 healthcare personnel from Al-Iman General Hospital in the Saudi government healthcare sector in Riyadh. The study utilized a questionnaire as the data collection tool. In light of this, the study reached several key findings, including a statistically significant positive linear relationship at a significance level of (0.01) between comprehensive quality standards and productivity level. This relationship indicates that focusing on implementing comprehensive quality standards increases the productivity level of healthcare staff in the Saudi government healthcare sector in Riyadh. Based on the results, the study recommends the necessity of Implementing comprehensive quality standards should be coupled with enhanced training programs for healthcare staff in government hospitals in Riyadh. These programs should focus on educating staff members about the importance of quality standards and how they can contribute to improving productivity levels. Establishing continuous quality improvement initiatives within government hospitals in Riyadh is essential. These initiatives should involve regular assessments of quality standards and productivity levels, with a focus on identifying areas for improvement and implementing appropriate measures to address them.