This research aims to study the impact of work burnout on the performance of health personnel in the government health sector in the Kingdom of Saudi Arabia. The study seeks to answer four main questions related to indicators of work burnout and its impact on work satisfaction and performance of health personnel, in addition to organizational factors and potential strategies to deal with this problem. The research objectives include determining the prevalence of work burnout and its factors in the Kingdom of Saudi Arabia, assessing its impact on work satisfaction and the quality of care provided, evaluating the effectiveness of available supports and interventions, in addition to proposing evidence-based strategies to prevent and manage work burnout among health personnel. The research aims to provide an effective contribution to understanding the challenges facing the government health sector in the Kingdom of Saudi Arabia and improving the work environment to ensure better performance of health personnel and the quality of care provided to patients.