The present research aimed to increase the solubility and dissolution rate of a poorly water soluble Aripiprazole (APZ) drug by a solid dispersion technique. Methods: Solid dispersions (SD) of APZ were prepared by fusion method using hydrophilic carrier Polyethylene glycol 6000 (PEG 6000) and co-carriers like, Croscarmellose sodium (CCS) and Crospovidone (CP) in different proportions and also prepared physical mixtures. These dispersions were characterized by in-vitro drug dissolution, Fourier transform infrared spectroscopy (FTIR) and Differential scanning calorimetry (DSC) studies. The optimized solid dispersion (6SD9) was formulated into fast-dissolving tablets (F1-F6) by direct compression method and evaluated for its pre and post compression parameters. Results: PEG 6000 physical mixtures containing Aripiprazole (6PM3), showed enhanced dissolution rate when compared with pure drug (APZ). Binary solid dispersions (6SD3) 59.32 % showed an improvement in the dissolution rate when compared to the Physical Mixtures (6PM3) 50.56% and pure drug (APZ) 17.38% drug release was resulted at the end of 60 min. From ternary solid dispersions with CCS, formulation code 6SD9 showed 92.62% and with CP, formulation code 6SD15 showed 73.34%, whereas pure drug showed 20.27 % drug release was resulted at the end of 60 min. So, based on the in-vitro dissolution studies of solid dispersions, the 6SD9 was selected to prepare tablets (F1-F6) by direct compression method using tableting excipients MCC and Mannitol as diluents and CCS, CP, SSG as super disintegrants. The prepared tablets were evaluated for its quality. From the results of dissolution studies of tablets, the formulation F3 95.25% showed rapid dissolution rate than other formulations and pure drug 20.27%. FTIR, DSC studies suggest that there was no physical and chemical interaction in between pure drug (APZ), carriers and co-carriers. Conclusion: Hence, the present study can conclude that ternary solid dispersions in association with super disintegrants were more effective in increasing the dissolution rate of poorly soluble drug than binary solid dispersions, physical mixtures and pure drug