The biodegradable industrial waste stream, with inhibiting COD concentrations for aerobic treatment requires anaerobic treatment in the first step. Anaerobic Fixed Bed Fixed Film Reactor (AFBFFR) is one of the simpler and high rate digesters in wastewater treatment. Synthetic fill media is used to hold the active bio mass in packing of fixed bed fixed film reactor. Sugar industry is one of the agro based industries located in rural areas. This reactor can be an appropriate option to upgrade the efficiency of the existing treatment plant. The present study was an experimental work carried out with a laboratory model on Anaerobic FBFF reactor for evaluating the biochemical processes and kinetic processes for treating biodegradable industrial waste streams. The study was conducted specifically for wastewater from sugar industries. The experimental results were used to evaluate the COD removal efficiency of the Anaerobic FBFF reactor and mathematical models were developed to characterize the biochemical process kinetics to enable the design of the Anaerobic FBFF reactor.