Tuberculosis is an infectious disease caused M. tuberculosis. The estimated 1/3 of the world’s population has been infected tuberculosis (TB) and has become the world severe cause of death (WHO 2018). India is a country where the highest number of people suffering from tuberculosis. Tuberculosis has been seen traditionally as poor man’s disease, but this no longer true in Assam. Objective: To study the affect of different socio-economic and demographic factors on awareness of Tuberculosis. Methods: This cross-sectional study took place from Jan. 2021 to Mar. 2021. It followed a descriptive, non-experimental research design with a quantitative measure to investigate awareness of TB patients in Dhemaji district, Assam. The majority of population had education upto Elementary level (34.62%) followed by secondary education Population containing 29.62%. Results: Here we have found that positive disease history is 68% more likely to be aware and this is found to be statistically significant. Again, persons in whose neighborhood TB is present are 23% more likely to be aware and this is found to be statistically significant and we found that 30-50 years age group persons are 1.5 times more likely to be aware than 70 & above people but it is not found to be statistically significant.