Aim: 1. To assess the knowledge regarding Telemedicine before Structured Teaching Programme among students. 2. To assess the effectiveness of Structured Teaching Programme on knowledge regarding Telemedicine. 3. To compare the knowledge before and after Structured Teaching Programme regarding Telemedicine among students. 4. To find out the association between the pre-test knowledge score regarding Telemedicine with selected socio-demographic variables. Material and method: Investigator adopted quantitative research approach with pre-experimental one group pre-test-post-test design. The subjects were 152 students of final year Basic B.sc Nursing and non-probability purposive sampling method was used for selection criteria. Data was collected using demographic data profile and self-structured knowledge questionnaire regarding Telemedicine. Data were analyzed using descriptive and inferential statistics.