To assess the effectiveness of self instructional discharge module on knowledge regarding lifestyle modification and prevention of complications among patients with first line cardiac problems. To assess the Pre and Post-test level of knowledge regarding lifestyle modification and prevention of complications among patients with first line cardiac problems. To determine the effectiveness of self instructional discharge module on knowledge regarding lifestyle modification and prevention of complications among patients with first line cardiac problems. To associate Pre-test level of knowledge regarding lifestyle modification and prevention of complications among patients with first line cardiac problems with their selected socio demographic variables.A Pre-experimental one group pre-test and post- test research design was adopted for this study. 50 samples were selected by using Non probability purposive sampling techniques. The pre-test and post-test level of knowledge was assessed by self structured knowledge questionnaires. The findings shows that Pre-test Mean score was 9.06 with a standard deviation of 4.27 and the Post-test mean score was 29.76 with a Standard deviation of 3.02, Mean difference is 20.7 with a standard error of 0.62 and t-test value was 33.38 shows high significance.The study concluded that the self instructional discharge module was effective in upgrading the knowledge of patients with first line cardiac problems regarding lifestyle modification and prevention of complications