Introduction: The need for environmental conservation and the prevention of toxic greenhouse gas emissions from power generation systems have led to an increasing interest in utilizing waste heat resources such as low grade heat (LGH) sources, which are abundantly available from various industries and commercial sectors. However, the current conventional power cycle processes have limitations in utilizing these resources to their maximum potential. Trans-critical carbon dioxide has been found to be an effective option for low temperature processes due to its numerous benefits, including its low cost and availability. When used in combination with refrigeration, trans-critical carbon dioxide in a combined power cycle has been found to perform better than when used alone. Further research is needed to explore the potential applications of this process. This review article aims to provide a systematic and scholarly overview of the application areas and thermodynamic analysis of the combined power cycle of trans-critical carbon dioxide with ammonia water mixture. The article intends to offer useful insights and evidence to support the development and expansion of the use of this process.