Ayurveda consider health and disease both as the essence of food and life style.Today whole world is changing and update with new technologies and modernization in this 21st century a lot of new diseases develops due to the inappropriate lifestyle, improper diet and unhealthy food, lack of exercise ,heavy work load leads mental stress and disturbs sleep due to shift duties .It was totally disturbs the biological clock of human being and leads many new life style disorders. Ayurveda consider this all thing in Apathyaahara and ViharaSevana .And the Ajirna(indigestion)(indigestion) is one of the most commonest disease which is originate from Agni.Due to all above mentioned factors leads digestive insufficiency(Agnimandya). Ajirna correlate with dyspepsia. Dyspepsia prevalence rate world wide is 20-30%, and in India it is 30-49%.Ayurveda always explains management and prevention of disease. Ayurveda gives prime importance to Agni as it is one of the basic biological element of the the living body. Agni has characteristics, location, function and secretions like digestive juices and enzymes which participate in the digestive and metabolic functions. Ayurveda consider Dehagni(digestive enzymes& secretions) as the cause of life ,complexion, strength, health, Oja, Teja and Prana .Ayurveda considers that no diseases ever develops without Agnimandya(digestive insufficiency). Ajirna(indigestion) develops as a result of less, excessive, and irregular digestion of food and long term of this condition production of Amadosha and it is circulate all over body.TheseAmadosha combined with other Doshas and Dushyas vitiated them and leads lot of disease also leads life threatening diseases.preventive measures like Dinacharya, Rutucharya, Ratricharya, Sadvritaand Pathya(Wholesome) palan and Ashtoaharvidhietc are the preventive measures for Ajirna(indigestion) in Ayurveda.