The aims of this study are to enhance the knowledge and attitude regarding prevention and management of COVID-19 among nursing students. The objective of study was to assess the level of knowledge and attitude regarding prevention and management of COVID-19 among nursing students, to assess the effectiveness of structured teaching programme on knowledge and attitude regarding prevention and management of COVID-19 among nursing students, to find the association between Pre-test level of knowledge and attitude regarding prevention and management of COVID-19 among nursing students with their selected demographic variables. A multiple-choice questionnaire was completed by 50 nursing students studying at Rohilkhand School of Nursing, Bareilly. The sample was selected by using the Non-Probability Convenient Sampling method. The data was collected by using multiple choice questionnaires. The result of study was According to age in 32(62.0%) of them belong to the age group between 17-19 years, 13(26.0%) of them belong to the age group between 20- 22 years, 4(8%) of them belong to the age group between 23-25 years, and 1(2.0%) of them belong to the age group between 25 years above. Regarding gender of nursing students 12(24.0%) were male and 38(76.0%) were female. Revealed the participants of education 50(100%) in Diploma, (0%) in graduate, (0%) in post graduate, and (0%) in other. Regarding the religion 1(2.0%) were Sikh, 44(88.0%) were Hindu, 1(2.0%) were christen, 4(8.0%), and (0%) were other religion. Regarding the participants of living area among the 39(78.0%) in rural area, 11 (22.0 %) urban in area. Distribution of nursing students to any previous knowledge on prevention and management of COVID-19, 46(92%) were yes, and 4(8%) were no. (38) In Distribution of nursing students, if we analyze them according to their sources of information among the 36(72%) were social media, 4(8.0%) were family and friends, 3(6%) were class room teaching and 7(14%) were other information about COVID-19.Interpreted the mean score of knowledge in pre-test was 25.86 and post-test was 36.08, standard deviation in pre-test was 2.82 and post test 3.43 and mean difference score was 10.22. Mean score of attitude in pre-test was 53.08 and post-test was 63.00, standard deviation in pre-test was 4.94 and post test 5.89 and mean difference score was 9.92.