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ISSN 2063-5346
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An in-depth look into Floating Formulations, an Innovative Approach to Drug Delivery

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S. B. Nagansurkar, Dr. Sanjay K. Bais, Dr. Yogesh B. Raut, Mr. Nilesh Sevak Dhavare, Mr. Ravikiran Preetam More, Miss. Pradnya Harshavardhan Gadhire, Dr. Sandip Babarao Sapkal, Mr. Sachin Hanumant Misal, Mr. Ganesh Kashinath Bahekar
» doi: 10.48047/ecb/2023.12.si4.1628

Abstract

The aim of developing new drug transport mechanisms is solving various flaws in traditional dosage formulations, also to resolve some concerns regarding physical and chemical properties of drug moieties & development of the formulation. The floating medicine delivery strategy is an effective technique for drugs with smaller absorption window, insoluble and slightly water-soluble pharmaceuticals, medications that are needed to be placed inside the stomach lumen as they show limited absorption from colon or degradability. Drug distribution system that floats operates underneath a drug delivery mechanism that lies in the stomach, which continuously controls the flow of drugs with limited solubility to the site of absorption. This article contains detailed information regarding floating drug administration systems, including advantages and disadvantages over conventional drug delivery systems, both of which are significant when designing dosages. This dosage form was created using a variety of methods. The effervescent floating drug delivery system's formulation and evaluation approaches were investigated. The goal of this comprehensive study is to combine all known studies on this distribution method. We investigate the several aspects that influence stomach retention and provide useful information on the formulation aspects to achieve it.

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