The clinical evaluation of patients with olfactory dysfunction should include a thorough history taking, physical examination, psychophysical olfactory tests, and/or imaging. There have been a few case reports for a natural history of spontaneous recovery from anosmia after post-URI and head trauma, mostly within the first year. Various medical treatments have been tried, including topical and systemic steroids may improve conductive, post-viral, and idiopathic olfactory loss. Topical steroids have been used as monotherapy or adjuvant therapy.Systemic steroids can restore many patients (83%) who still complained smell loss after endoscopic sinus surgery but long-term prognosis is less promising. Platelet-rich plasma is defined as a plasma fraction of autologous blood having platelet concentration above baseline, and prepared from blood drawn from the patient. Following the application of PRP in the olfactory area of 5 patients with idiopathic anosmia in 4 sessions, the sense of smell returned in 4 patients, and one patient stated that he could smell a little but could not smell all. In a similar study conducted in 2020, although there was no significant improvement in Sniffin Sticks score in 2 patients with anosmia, it was observed that all 5 patients with hyposmia reached normosmia after 3 months of follow-up.