Autoimmune illnesses typically present themselves with oral symptoms as their initial manifestation. As a result of this, dentists play a significant role in the identification of newly emerging autoimmune disorders. As a matter of fact, a timely diagnosis has the potential to significantly contribute to the enhancement of both the quality of treatment options and the quality of life. Having a specialized understanding of the oral symptoms of autoimmune disorders is necessary in order to acquire this expertise. The purpose of this article is to provide a description of the oral manifestations of many autoimmune disorders, including systemic lupus erythematosus, celiac disease, Sjogren syndrome, pemphigus vulgaris, and Behcet disease, among others