Nanofibers are strong strands with measurement from few nanometers to 1000nm, with hypothetically limitless length. Nanofiber displays supported medication discharge inside the body to treat any ailment. Nanofiber turned out to be progressively significant for development of disintegration and bioavailability of inadequately dissolvable medication. The point of this paper is to sum up the procedures for the improvement of nanofiber and their different applications. This paper revolves around the sorts of composite nanofiber, synthesis of nanofiber, polymers, solvents and excipients utilized in the fabrication of nanofiber. The benefits and restriction of nanofibers are likewise examined. Among a few methods of nanofiber creation, electrospinning is generally proficient and a practical procedure. Biomedical applications like wound dressing for skin recovery, foundational microorganism transplantation or medication conveyance require uncommon interest on three-dimensional permeable platform.