Depression occurs without a history of manic, mixed, or hypomanic episode. Depression episode must last at least 2 weeks, and typically a Person with a diagnosis of a depression may experience at least four Symptoms; from a list that includes changes in appetite and weight, changes In sleep and activity lack of energy, feeling of guilt, problems thinking and Making decision, and recurring thoughts of death or suicide. Dr. Hahnemann has also paid attention towards mental illness and he was the first physician who told mentally ill patient sick individual who requiring empathy and proper Medical care. According to him, mind and body are not two separated Entities. Also master had treated many patients having mental illness and he has described this as psycho – somatic disorders. Somato – psychic disorder, Emotional diseases and mental diseases of doubtful origin and management of these disorder he had described in §210-230.i.e. friendly exhortation, sensible advice etc[1].