.

ISSN 2063-5346
For urgent queries please contact : +918130348310

ANALYTICAL METHOD DEVELOPMENT AND VALIDATION OF FIMASARTAN BY USING UV-VISIBLE SPECTROPHOTOMETRIC METHOD

Main Article Content

Anuja Bhosale, Priyanka Sanap, Rupali Patil, Suvarna Katti
» doi: 10.53555/ecb/2022.11.12.223

Abstract

For the determination of Fimasartan in pharmaceutical dosage forms, a straightforward, focused, accurate, and precise UV spectrophotometric approach was created and validated. The correlation was 0.9991, and the linearity was concentration range of 3-18 µg/ml. It was discovered that the regression equation was Y=0.0429x + 0.0034. Linearity, accuracy, precision, the limit of detection, the limit of quantitation, and the robustness of the method were all validated. The LOD and LOQ for estimation of Fimasartan were found to be 0.047 µg/ml and 0.144 µg/ml, respectively. Recovery of Fimasartan was found to be in the range of 98.37- 100.92 %. The challenges of this research work of UV method development for Fimasartan include the need for precise and accurate measurement of the drug’s concentration and the potential interference from impurities or other substances in the sample. The contributions made in the research work of UV method development for Fimasartan include the establishment of a reliable and efficient method for determining the drug’s concentration in various samples, which can aid in its formulation, quality control and pharmacokinetic studies. Additionally, this method can contribute to the development of new drug delivery systems and dosage forms for Fimasartan. The proposed method for quantifying Fimasartan in pharmaceutical dosage form was effectively used.

Article Details