Introduction: Bodybuilders often experience shoulder muscular soreness after exercising. Fatigue may adversely harm an athlete's shoulder joints and reduce performance quality. In this research, teenage bodybuilders were tested to see how exhaustion affected their ability to exert force with their abductor, retractor, flexor, depressor, elevator, and extensor muscles after a period of crippling fatigue. Methods: 25 active bodybuilders (age: 26.122.78 years, height: 1.820.035 m, weight: 78.924.23 kg, BMI: 23.711.40 kg / m2, and sports history: 2.960.97 years) were chosen for this quasi-experimental research using a pre-test and post-test design. Using a portable tensile-compression tachometer, the force of the shoulder's flexor, extensor, elevator, depressor, retractor, and abductor muscles was measured before and after the exhaustion. The paired samples t-test was performed to compare the fatigue regimen in order to examine the statistical component. Results: The study's findings revealed that a recurrence of crippling tiredness decreased the force of the shoulder muscles' flexor (P=0.001), extensor (P=0.001), an elevator (P=0.001), depressor (P=0.001), retractor (P=0.001), and abductor (P=0.001) fibers. Conclusions: In general, the findings of the present study demonstrated the impact of fatigue on the reduction of the flexor, extensor, elevator, depressor, retractor, and abductor muscles of the shoulder. This force decrease can be a factor in lowering performance quality in conditions of fatigue and possibly raising the risk of injury in athletes.