Background: Chewing tobacco, areca nuts, and their related products can develop oral submucous fibrosis (OSF), a premalignant disease with a high rate of malignant transformation. Due to the increased processing and marketing of areca nut products, which is frequently found in younger age groups, OSF is more prevalent in India and Southeast Asian nations. Clinical signs of OSF, such as constricting bands of collagen in the buccal mucosa, inflammation, and trauma that result in the development of fibroblasts and fibrosis, are used to make the diagnosis and histopathology for confirmation. It has been demonstrated that the main function of herbs and the substances they contain is to stop excessive and aberrant fibrosis in a variety of fibroproliperative disorders