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ISSN 2063-5346
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ANTI PSORIATIC POTENTIAL OF SYNTHETIC AND HERBAL ANALOGUES WITH SPECIAL REFERENCE TO BLACK CUMIN

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Priyanka Jain1, Rama Tyagi2, Swati Madan3, Maryam Sarwat4, Shikha Saxena5, Anshul Gupta6, Ramanpreet Walia7*
» doi: 10.48047/ecb/2023.12.si5a.0555

Abstract

Histologically, the skin condition known as psoriasis is characterized by aberrant differentiation and hyperproliferation of epidermal keratinocytes. Psoriasis is a condition that has some known conventional medical therapies, including phototherapy, systemic medications, and various combinations of those. The bulk of these therapies do, however, have some efficacies as well as possible drawbacks, which restrict their long term use. Skin atrophy, organ toxicity, carcinogenicity, and broad spectrum immunosuppression are some of these adverse consequences. Therefore, using herbal products as a psoriasis alternative treatment that has fewer side effects would be better. The goal of the current study is to consolidate the available information on synthetic, herbal, and polyherbal medications for the treatment of psoriasis including a special emphasis on Black cumin. Incorporating phytocomponents extracted from various plants that exhibit anti psoriatic activity has been attempted in this review. To fully utilize these plants as prospective anti psoriatic medications, a comprehensive exploration of these plants is required to extract anti psoriatic ingredients and assess their potential mechanisms of action. Finally, we provide a comprehensive examination of popular, well known synthetic and therapeutic plants and known anti psoriatic activities of black cumin. Additionally, this enables various studies to examine the efficacy of different herbal remedies for the management of skin diseases like psoriasis.

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