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ISSN 2063-5346
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Antimicrobial activity and bio-film inhibition potential of selected heterocyclic compounds

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Chirra Ramakrishna, P.T.S.R.K.Prasada Rao, Srikanth Inturi
» doi: 10.53555/ecb/2022.11.4.030

Abstract

Novel heterocyclic compounds indenoquinoxaline-11-one (QN)and4-[2-pyrimidinyl-2-phenylQuinazolin-4(3H)-one(Q-2APy) synthesized and investigated for anti-bacterial activity against Staphylococcus aureus and Multidrug resistance Staphylocoocus aureus (MRSA), Synthesized compounds also investigated for bio-film activity against above tested bacteria SA to explore antibacterial potency. Both QN and Q-2APY inhibits SA and MRSA bacteria. Both compounds had inhibition of bio-film produced by MRSA, but not with SA.

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