Mixtures of various Zeolite derivatives Viz; Propolis-Zeolite (PZ), Silver-Zeolite (SZ), and Silver- Sulfadiazine- Zeolite (ASZ) were applied as Matrix into commercial epoxy resin. The obtained coating materials were coated on MS steel panels. The uncoated materials were also taken in powder form. The antimicrobial activity of coated MS steel panels and of powder were evaluated by Agar cup method. The common bacteria Staphylococcus aereus, Streptococcus pyrogenaes, Escherichia Coli., Pseudomonas aeruginos and fungi Aspergillus Niger, Aspergillus Flavus, Penicillium expansum, Candida albicans, Rhizopus nigrieuns, Botrydepladia theobromine were used. The result show that the coating materials have excellent antimicrobial activity. The results indicate that such coating material can be used as food packaging materials