Volume - 13 | Issue-1
Volume - 13 | Issue-1
Volume - 13 | Issue-1
Volume - 13 | Issue-1
Volume - 13 | Issue-1
Anxiety includes worry and apprehension like symptoms. Women experience higher rates of emotional anxiety than men do when they are teenagers. Epilepsy is a group of disorder of brain with common, sudden and paroxysmal cerebral dysrhythmia with convulsions followed by affected consciousness. The name teak refers to the wood of the Tectona grandis plant. It is a significant plant because it's used as medicine in many different indigenous systems. Alkaloids, phenolic glycosides, steroids, etc., are just few of the many identified phytoconstituents. The current study was based on the anxiolytic and anticonvulsant evaluation studies of methanolic extract of Tectona grandis bark using different parameters in animal model. Drugs were procured from Sigma Aldrich and some chemicals from local sellers. The bark of plant was harvested at MJP University, Bareilly they were identified and authenticated at the herbarium section of the department of plant science, MJP university. The barks were prepared by using Soxhlet and simple maceration methods. After extraction, it was evaluated for phytochemicals like alkaloids, glycosides etc. OECD guidelines 423 was followed for the dose selection of the extract. Anticonvulsant activity was evaluated in Actophotometer using PTZ induced model and anxiolytic activity in elevated plus maze. In results, the extract of Tectona grandis demonstrated a marked reduction in convulsion and anxiety in animals when compared with the control group. In conclusion, Tectona grandis plant’s bark might be used in the prevention and cure of epilepsy and agitation induced anxiety. It suggests to isolate the active principles and mode of action responsible for the pharmacological activity.