Introduction: Artificial Intelligence has emerged as a transformative technology with widespread applications across various sectors, including healthcare. Purpose: This review's objective was to aggregate the literature about Artificial Intelligence implementation and its effects on health within the Kingdom of Saudi Arabia, with an emphasis on nursing careers. The main goal was to find out what the present state of Artificial Intelligence in healthcare is and what the challenges and opportunities are in the Saudi Arabian healthcare landscape. Method: The study was carried out through a thorough search strategy that gave prominence to the studies undertaken in Saudi Arabia, which concentrated on Artificial Intelligence applications in health care, nursing, and their allied areas of interest. As inclusion and exclusion criteria were used to pick studies and conduct a quality assessment, data extraction came into play. Results: The results revealed that the research related to artificial intelligence applied in Saudi Arabia was growing and covered different domains such as healthcare, software engineering, cybersecurity, decision support systems, and pandemic response. These works highlight the use of Artificial Intelligence tools such as telehealth and clinical decision support systems. We can see that the potential for facilities is to help increase accessibility, efficiency, and costs of care. Conclusion: The report showed that Artificial Intelligence marked the advent of a revolution in nursing practice in Saudi Arabia. However, the challenges prompted by cultural perceptions, infrastructural readiness, and laws had to be addressed promptly.