Background: Infectious disease is a significant public health concern in both industrialized and poor countries. Infectious diseases cause huge population losses in India each year. Among infectious diseases, TB is the leading cause of death in both children and adults worldwide. Despite the fact that the causal organism was discovered more than 100 years ago and very potent medications and vaccinations are available, tuberculosis (TB) remains a worldwide public health problem. Eleven of the 22 high-burden TB countries are in Asia, while nine are in Africa. These countries account for almost 80% of all cases worldwide. India has a large burden in Asia, accounting for roughly 20% of the world burden