Mangroves are a distinctive woody plant community that can be found on tropical and subtropical intertidal shores. The mangrove ecosystem, which is still completely unexplored, has tremendous opportunities for discovering unusual actinomycetes with distinctive characteristics that are capable of creating a variety of novel bioactive chemicals, including enzymes, antibiotics, and anticancer agents. Mangrove ecosystems are among the most productive and have special environmental characteristics, although they have received the least attention. Mangrove soil-isolated actinomycetes have been shown to generate antimicrobials, antivirals, antioxidants, and anticancer chemicals in addition to industrial enzymes like lipase, cellulase, protease, and pectinase. The majority of the aerobic actinomycetes are gram-positive, filamentous, branching bacteria that develop slowly and are only partially acid-fast. Actinomycetes are capable of producing a wide range of biologically active secondary metabolites, including cosmetics, vitamins, food additives, antibiotics, insecticides, anti-parasitic agents, and enzymes.