Deep vein thrombosis (DVT) is a serious condition that can be life-threatening. However, it’s largely preventable and treatable if discovered early. In recent years, great effort has been made to establish risk assessment models (RAMs) to identify patients with high and low risks for various outcomes. Present study was aimed to study assessment of risk of deep vein thrombosis among patients admitted in ICU by risk analysis scoring at a tertiary care center. Material and Methods: Present study was single-center, point prevalence study, conducted in patients admitted in ICU, patients analysis done once a week. A structured proforma was designed for risk assessment and stratification of DVT risk was calculated as per risk analysis score. Results: In present study, 100 patients were screened. Majority were from 50-59 (25 %) & 70-79 years age group (20 %), were male (66 %) & had normal BMI (18-25 kg/m2) (59 %). Among study patients, common provisional diagnosis were AKI on CKD/with sepsis (19 %), pneumonia (11 %), malignancy (13.33 %) & CKD with/without sepsis (10 %). Total no of high risk cases deserving prophylaxis were 70 (70 %) (highest & high risk), others were moderate (17 %) & low-risk (13 %). 82 patients (82 %) received deep vein thrombosis prophylaxis. Common reasons for not giving prophylaxis (n=18) were low platelet count (55.56 %), active bleeding (27.78 %), Early ambulation (11.11 %) & on hemodialysis (5.56 %). Among study patients, no DVT observed, thus 100 % success observed among who received DVT prophylaxis according to risk scoring analysis. Conclusion: Risk analysis scoring is helpful to improve assessment of risk of deep vein thrombosis among patients admitted in ICU compared with usual practice.