This work proposes a plan for air quality management in Ben Tre province (Vietnam) based on conducting the assessment of the current status and evolution of air quality in Ben Tre province using AERMOD dispersion model with monitoring and surveying data. The results of the assessment and forecast of the current status of air quality by 2030 show that transportation is the main source of air pollution in Ben Tre province. The emission rate is relatively high, but in general, it still meets air quality standards. The results of the actual survey in households and simulations by the AirQ+ model on the impact of air pollution on public health show that air pollution has a negative impact on public health with a high risk of respiratory and cardiovascular diseases. The management and treatment of air pollution in the province are well-concerned, coordinated, and implemented by management agencies. After considering the effectiveness analysis of environmental protection, this study has analyzed and proposed priority solutions for the implementation of the air quality management plan in the province until 2025 and proposed content and priority for the implementation of the plan in the period of 2022 – 2025.