Bronchial asthma is becoming increasingly common, especially in youngsters, and this is a major public health issue. About 300 million individuals worldwide are affected by it. A suggested association was reported between bronchial asthma and thyroid disorders. The purpose of this research was to examine whether or not children with asthma are more likely to have thyroid problems. Patients and Methods: Sixty bronchial asthmatic children participated in the current investigation in addition to 30 apparently healthy children. Assessment of the degree of asthma severity and detection for the presence of other atopic conditions were done. Assessment of the thyroid function with evaluation of anti-thyroid peroxidase (TPO) enzyme in addition to performing of different allergic skin tests in the asthmatic cases. Results: In comparison to the control group, those with asthma had significantly greater levels of thyroid stimulating hormone and significantly lower levels of thyroid hormones overall. The TPO level was statistically significaly higher in the asthma group. Anti TPO enzyme levels were significantly inversely related to T3 levels. Anti TPO enzyme > 16.80 had a sensitivity of 73.3% and a specificity of 66.7% in detecting instances of atopic bronchial asthma. Conclusion: A higher level of Anti TPO enzymes is indicative of an autoimmune component in bronchial asthma, and this is linked to hypothyroidism in the affected children. Thyroid disorders were more common when the underlying disease was more severe and the patient responded less well to treatment