As per the texts of Ayurveda, origin of this disease is from Ama – the undigested/ Incompletely metabolized metabolic products. Consumption of Incompatible food and improper physical activities are said to play key roles in manifestation of Amavata. Main features are said to be joint swelling with pain and deformity in chronic stages. Rheumatoid arthritis is a chronic systemic autoimmune inflammatory disease that is seen more frequently in females than males. Concerns regarding the safety and expenditure of conventional arthritis therapies have given emphasis on usage of natural remedies. Therefore, here we report a case of Chronic RA which was successfully managed by Ayurvedic interventions only. On assessment of Nidanas, vitiation observed was SamaVata and SamaPitta. Dushyas involved were Rasa, Rakta, Asthi, and Manas. Sanga was the Srotodushti prakara. Ayurvedic interventions like Rukshana, Langhana, Snehana and Rasayana were administered. Patient had significant improvement in the complaints and during a follow-up of 6 months, disease did not aggravate and Quality of Life was significantly improved.