As a member of the Meliaceae family, neem (Azadirachta indica) is a rich source of antioxidants. In general, it has been used extensively in Chinese, Ayurvedic, and Unani prescriptions, especially in the Indian Subcontinent for the treatment and preventative activity of many illnesses. 140 distinct mixes may be created using different portions of neem. All components of the neem tree, including the leaves, flowers, seeds, organic products, roots, and bark, have historically been used to treat irritability, contaminations, fever, skin conditions, and dental problems. Neem leaf's medicinal benefits have been highlighted in particular. Immunomodulatory, relaxing, antihyperglycemic, antiulcer, antimalarial, antifungal, antibacterial, antiviral, cell-reinforcing, antimutagenic, and anticarcinogenic activities of neem leaf and its components have been demonstrated.